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Latest update: February 8, What's the difference between the various Covid vaccines available in France? How will getting inoculated work? And what happens after the jab? France's vaccination campaign has raised a wealth of questions. Available first to nursing home residents and healthcare professionals over 50 years of age, the government extended vaccinations to people over 75 and anyone at high risk for Covid starting January The country approved a third vaccine for use in February and aims to vaccinate everyone who wants a jab by summer's end.
What vaccines are available in France and what are the differences between them? The latter ed France's stable of approved Covid vaccines most recently, with the first doses administered to healthcare professionals under the age of 65 on February 6.
France will allow the AstraZeneca vaccine to be administered by pharmacists. The difference between the vaccines lies primarily in how they need to be stored. Researchers have said they are not concerned about effectiveness against the new strain first detected in the United Kingdom but the South African variant has raised more questions.
Meanwhile, a strain detected in Brazil and Japan is "the most worrying of all", Ravi Gupta, a professor of clinical microbiology at the University of Cambridge, told AFP. Indeed, tests show that the variant could possibly escape from the antibodies meant to neutralise it, sidestepping the body's natural defence memory and the immunity that comes with it. US biotechnology firm Moderna said on January 25 that lab studies showed its Covid vaccine remained effective against variants of the coronavirus first identified in the UK and South Africa.
That positive news was somewhat tempered by the finding a six-fold reduction in the level of highly potent neutralising antibodies produced against the South African variant B. The company said it would try adding a second booster of its vaccine — meaning three shots in total — "out of an abundance of caution" and has begun preclinical studies on a booster specifically for the South African variant. South Africa suspended the start of its inoculations with the AstraZeneca vaccine on February 8 after a trial showed it provided only "minimal" protection against mild to moderate Covid caused by the variant first detected in that country.
AstraZeneca told AFP it believed its vaccine would still protect against severe disease and said researchers were already working to update the vaccine to tackle the South African variant. The of the France days wanted asap 49 49 1 and 2 trials unveiled in December of the vaccine developed by the French multinational Sanofi France days wanted asap 49 49 positive for adults between the ages of 18 and 49, but the immune responses elicited in older subjects were deemed disappointing.
According to Sanofi, a new trial with "an improved antigen formula" is set to begin in February.
The third phase will not be able to begin before the second half ofhowever, which pushes back the vaccine's eventual availability on the market to the end of this year, at best. On January 25, France's Pasteur Institute, named for 19th-century French vaccine pioneer Louis Pasteur, announced it was ending development of a vaccine it was working on based on an existing measles vaccine with US pharmaceutical firm Merck after clinical trial proved disappointing. The institute stressed it would be continuing its work on two other vaccine projects using different methods.
I've already had Covid Do I need to get vaccinated? Someone who has already contracted Covid could still benefit from the vaccine, even if "the risk, even theoretical, among those people appears In such cases, one must respect a minimum three-month wait after the onset of symptoms and not present persistent symptoms.
No, not unless there has been contact with someone who is sick. In the case of a Covid infection, after consulting with one's doctor, waiting three months after the onset of symptoms is enough. France's HAS has listed the most frequent episodes reported in the seven days following the first injection. With the Pfizer-BioNTech Cominraty vaccine, the France days wanted asap 49 49 frequently observed side effects are soreness at the site of the injection in 80 percent of casesfatigue in more than 60 percent of casesheadaches in more than 50 percent of casesas well as muscle pain and chills.
However, these side effects were seen as mild and wore off in under 48 hours. With the Moderna vaccine, the main reactions observed also include soreness at the point of injection more than 90 percent of casesfatigue 70 percentheadaches more than 64 percent and muscle pain more than 61 percent.
During the Pfizer-BioNTech vaccine trials, out of the more than 43, people taking part in Phase 3 testing, four participants developed temporary facial paralysis, the causes of which are still being investigated, That was also the case for four participants in the Moderna vaccine trials three in the vaccinated group, one in the placebo group out of more than 30, people taking part in those tests.
Overall, about 10 serious side effects were recorded during the trials. The agency has committed to publishing the data collected by drug safety authorities on a weekly basis. The updates can be viewed in French here. As is the case with all medicines, doctors and pharmacists must report any negative side effect suspected of being related to the vaccine.
Moreover, it is possible for a patient to al potential concerns directly to their regional drug safety authority CRPV or report them online. Multiple authorities, including Epi-Phare, are carrying out studies on those who receive vaccinations in order to identify possible side effects. There is no clear answer to this question as yet, although some data on the matter is promising. The Moderna vaccine, in particular, saw a lower of asymptomatic patients 0. For AstraZeneca, a half-dose of the first injection protected recipients against asymptomatic infections by 58 percent. However, further studies need to be carried out to answer the question with certainty.
No adverse side effects were reported in pregnant women who took part in the clinical trials, be it with regard to the pregnancy itself or in the development of the foetus during the preclinical trials led by Pfizer and Moderna on animals. However, pregnant women are currently excluded from the vaccination campaign while targeted studies are conducted. According France days wanted asap 49 49 the European Medicines Agency, vaccination will only be considered once the expected benefit exceeds the potential risk. Why are the elderly first to be vaccinated? The French government aims above all to ease the pressure on hospitals.
Their strategy therefore is to prioritise those most vulnerable to Covid and those most susceptible to developing serious forms of the illness. Older people have been the primary victims of Covid since the start of the pandemic last year. Professionals working in nursing homes and presenting a high risk those above the age of 50 or suffering from other conditionsFrance days wanted asap 49 49 professionals including those in private practice, firefighters, home care workers over the age of 50 or with existing medical conditions, are also among those considered priority candidates for Covid vaccination in France.
Indeed, France days wanted asap 49 49 resident in facilities are those most at risk for serious forms of the illness and these locations are known to be places where the virus circulates quickly," the health ministry has said. Professionals working in such facilities are therefore particularly exposed. As of January 18, people over 75 who live independently, as well as high-risk individuals under the age of 75, are also eligible for the jab.
As French Prime Minister Jean Castex announced on January 14, more thanpeople "suffering from particularly serious illnesses" can now receive the vaccine. The official list also includes people suffering from certain rare illnesses. It reached the million mark on January 23, according to health ministry figures. By February 6, more than 1. He told TV channel TF1 that the of people vaccinated in the country would progressively increase to "4 million at the end of February, 9 million in March, 20 million at the end of April, 30 million at the end of May, 43 million at the end of June, 57 million at the end of July, and 70 million, that is to say the entire French population, by the end of August".
He cited limitations on the pharmaceutical industry's capacity to produce vaccine doses in massive quantities. On February 2, French President Emmanuel Macron promised that everyone in France who wants to be vaccinated against Covid would be offered a shot by the end of the summer, which is to say September In the interview broadcast on TF1, the French leader also said that the 80 percent of nursing home residents who wish to be vaccinated somepeople will have their wish fulfilled by "the beginning of March".
He said the country's vaccination campaign is "unfolding at the pace that was planned". In addition, manufacturers must first obtain authorisation for the lower agewhich have not yet participated in clinical trials. Pfizer-BioNTech does not have authorisation for its vaccine to be administered to anyone under the age of 16, while recipients of the Moderna vaccine must be 18 or older.
The former began a trial in October on participants aged between 12 and 15; the latter has yet to recruit candidates for its trial of 3, volunteers aged 12 to What about setting up a "vaccine passport"? Even though the French government has repeatedly said the Covid vaccine will not be mandatory, a potential "vaccine passport" could both break that promise and raise questions around personal freedom. Face masks remain mandatory even after vaccination and those inoculated must maintain social distancing.
Studies are under way to explore the capacity of antibodies induced by the vaccine to rapidly project through nasal mucus before France days wanted asap 49 49 virus can replicate there and be transmitted through the air to another person. France's transport minister said on January 11 that the answer to that was leaning towards "no". For the moment, in any case, no country is asking for a document proving one's Covid vaccination status as a condition for entry.
The World Health Organization WHO has said it is opposed "for the moment" to introducing Covid vaccination certificates as a condition for entry to international travellers. Two factors will also be pertinent going forward: The duration of immunity that Covid vaccines induce and the evolution of the virus.
Indeed, if the body were no longer able to recognise certain strains of the virus, the vaccine would need to be updated, which would mean requiring subsequent vaccinations.France days wanted asap 49 49
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